Innate Immunity, Inflammation and Nanosafety
Group Leaders :
Diana Boraschi , Paola Italiani
Institute of Biochemistry and Cell Biology
Contact
Diana Boraschi diana.boraschi@ibbc.cnr.it
Paola Italiani paola.italiani@ibbc.cnr.it
+39-081-6132314 (office) | +39-081-6132367 (lab)
Institute
Institute of Biochemistry and Cell Biology
Via Pietro Castellino 111 , 80131 Napoli
Tel. 0816132273
http://www.ibbc.cnr.it
Member’s Lab
Annunziata Corteggio (researcher) annunziata.corteggio@ibbc.cnr.it
Daniela Melillo (researcher) daniela.melillo@ibbc.cnr.it
Activities
- Mechanisms of activation and polarisation of human monocytes and macrophage-derived macrophages
- Mechanisms of induction and modulation of innate memory of monocytes and macrophages
- Role of inflammatory cytokines in chronic inflammatory, immune-related and degenerative diseases
- Biology of IL-1 family cytokines
- Immunosafety of engineered nanoparticles, with focus on innate immunity, inflammation, and innate memory.
- Evaluation of innate memory induction and modulation in the marine invertebrate Ciona intestinalis
- In vitro tissue-like 3D models for studying human macrophage functions.
Partners
- Lab with the Lab of Invertebrate Immunology and Nanosafety (Institute for Biomedical Research and Innovation – IRIB-CNR, Head: Dr Annalisa Pinsino)
- Joint Lab with the Lab of Evolution of Immune System (Institute of Biochemistry and Cell Biology – IBBC-CNR, Head: Dr Maria Rosaria Coscia)
- University of Salzburg
- University of Pisa
- University of Catania
- Catalan Institute of nanoscience and nanotechnology
- Stazione Zoologica “Anton Dohrn”
- European Commission, Joint Research Centre, Ispra (IT)
Project
- PRIN 2017 “NanoTechVax Tackling biological barriers to antigen delivery by nanotechnological vaccines”. Prot. 20173ZECCM.
- H2020 ETN project “ENDONANO: Quantitative detection of bacterial ENDOtoxin by novel NANOtechnological approaches”. H2020-MSCA-ITN-2018 – EID- 812661.
- PNRA 2018 “Impact of the Antarctic environments on human homeostasis, psychology, physiology and immunology”
- PNRA 2016 “Effects of extreme environments on psychophysiology, energy metabolism and immunity: neuropsychological, immunohistochemical, proteomic and fMRI studies”
Istrument & technologies
- PRIN 2017 “NanoTechVax Tackling biological barriers to antigen delivery by nanotechnological vaccines”. Prot. 20173ZECCM.
- H2020 ETN project “ENDONANO: Quantitative detection of bacterial ENDOtoxin by novel NANOtechnological approaches”. H2020-MSCA-ITN-2018 – EID- 812661.
- PNRA 2018 “Impact of the Antarctic environments on human homeostasis, psychology, physiology and immunology”
- PNRA 2016 “Effects of extreme environments on psychophysiology, energy metabolism and immunity: neuropsychological, immunohistochemical, proteomic and fMRI studies”