Mario Galgani

mario.galgani@unina.it

39-0817464580 | 39-0817464596

Institute
Institute of Endotypes in Oncology, Metabolism and Immunology
Via Sergio Pansini, 5 – 80131 Napoli (NA)
Tel. 0817704795
http://www.ieos.cnr.it/

• Claudia La Rocca, PhD (CNR contract)
• Sara Bruzzaniti, (CNR contract)
• Monica Napolitano (Student)
• Salvatore De Simone (CNR senior technician)
• Maria Rosaria Montagna (CNR technician)

Main scientific interest of Dr. Galgani is focused on the comprehension of the biological and molecular mechanisms regulating the immune system in both physiological and pathological conditions. In particular, his main interest concerns the study of the pathogenic mechanisms leading to the alteration of immune tolerance during autoimmune diseases, such as Type 1 Diabetes (T1D). Dr. Galgani aims at studying the functional characteristics of regulatory T cells (Treg) a specific CD4⁺ T cell population involved in the control of immune tolerance.  Specifically, the research is focused on the study of the link between metabolic programs (glycolysis and FAO) and Treg cells. In addition, the research area of Dr. Galgani is also focused on the comprehension of pathogenic mechanisms at the basis of T1D, and, in particular, on the identification of novel regulatory cell population and biomarkers reflecting diabetes progression. Finally, Dr. Galgani’s research is also aimed at understanding the impact of inflammation on the immunological dysregulation observed in cancer.

• Flow Cytometry
• Cell sorting
• Seahorse Technology
• Luminex technology
• Western Blotting
• biochemical assays