Luca Businaro

luca.businaro@cnr.it

Istitute
Institute of Photonics and Nanotechnologies – Rome Branch
Km. 29.500 Via Salaria,  Montelibretti, RM 00015
www.ifn.cnr.it

Luca Businaro, Adele De Ninno, Francesca Roman Bertani, Farnaz Dabbagh Moghaddam

Organ on chip approach to develop advanced in-vitro biological models, with particular focus to onco-immunology. Interoperability of in-vitro and in-silico models

• Vacchelli et al.  2015, “Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1”, Science, vol. 350, no. 6263, pp. 972-978.
• V. Lucarini et al., “Immunogenic Cell Death Inducers in Cancer Immunotherapy to Turn Cold Tumors into Hot Tumors,” International  Journal of Molecular Sciences 26 (2025): 1613, https://doi.org/10.3390/ijms26041613.11
• S. Ielpo, F. Barberini, F. Dabbagh Moghaddam t al, “Crosstalk and communication of cancer-associated fibroblasts with natural killer and dendritic cells: New frontiers and unveiled opportunities for cancer immunotherapy,” Cancer Treat. Rev. 131, 102843 (2024). https://doi.org/10.1016/j.ctrv.2024.10284325
• Parlato et al. 2017, “3D Microfluidic model for evaluating immunotherapy efficacy by tracking dendritic cell behaviour toward tumor cells”, Scientific Reports, vol. 7, no. 1.112
• Biselli et al 2017, “Organs on chip approach: A tool to evaluate cancer-immune cells interactions”, Scientific Reports, vol. 7, no. 1.

Lithography and additive manufacturing