Businaro’s Lab
Group Leader: Luca Businaro
Institute of Photonics and Nanotechnologies – Rome Branch
Key words: organ on chip, microfluidics, micro and nano fabrication, ontologies
Contact
Luca Businaro
Institute
Institute of Photonics and Nanotechnologies – Rome Branch
Via fosso del Cavaliere 100 – 00133 Roma
www.ifn.cnr.it
Lab Members
Luca Businaro
Adele De Ninno
Francesca Roman Bertani
Farnaz Dabbagh Moghaddam
Activities
Organ on chip approach to develop advanced in-vitro biological models, with particular focus to onco-immunology. Interoperability of in-vitro and in-silico models
Key Publications
- Vacchelli et al. 2015, “Chemotherapy-induced antitumor immunity requires formyl peptide receptor 1”, Science, vol. 350, no. 6263, pp. 972-978.
- V. Lucarini et al., “Immunogenic Cell Death Inducers in Cancer Immunotherapy to Turn Cold Tumors into Hot Tumors,” International Journal of Molecular Sciences 26 (2025): 1613, https://doi.org/10.3390/ijms26041613.11.
- S. Ielpo, F. Barberini, F. Dabbagh Moghaddam t al, “Crosstalk and communication of cancer-associated fibroblasts with natural killer and dendritic cells: New frontiers and unveiled opportunities for cancer immunotherapy,” Cancer Treat. Rev. 131, 102843 (2024). https://doi.org/10.1016/j.ctrv.2024.10284325.
- Parlato et al. 2017, “3D Microfluidic model for evaluating immunotherapy efficacy by tracking dendritic cell behaviour toward tumor cells”, Scientific Reports, vol. 7, no. 1.112.
- Biselli et al 2017, “Organs on chip approach: A tool to evaluate cancer-immune cells interactions”, Scientific Reports, vol. 7, no. 1.
Instrument & technologies
Lithography and additive manufacturing