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Silvia D’Amico Lab

Contact

Silvia D’Amico


+39 0649934715 / 3388294339
damico@cnr.it

Institute
Institute of Translational Pharmacology
Via Fosso del Cavaliere 100 – 00133 Roma

Tel. +39 06 45488486 

http://www.ift.cnr.it

Activities
  • Dissection of tumor immune heterogeneity and crosstalk between tumor and immune cells.
  • Development of new strategies for local modulation of the tumor immune microenvironment and enhancement of tumor immunogenicity.
  • Development of combination therapies to extend the area of efficacy of current immunotherapeutic approaches
Istrument & technologies
  • Cell isolation and culture
  • CRISPR/Cas9 gene editing
  • Gene expression (real-time PCR)
  • Protein expression
  • Establishment of mouse and/or patient-derived organotypic tumor spheroids
  • Multicolor flow cytometry for tumor microenvironment dissection
  • In vitro tumor-immune interaction studies (evaluation of activation status, migration, effector function, proliferation)
Network