
Silvia D’Amico Lab
Group Leader : Silvia D’Amico
Institute of Translational Pharmacology – Rome
Contact
Silvia D’Amico
+39 0649934715 / 3388294339
damico@cnr.it
Institute
Institute of Translational Pharmacology
Via Fosso del Cavaliere 100 – 00133 Roma
Tel. +39 06 45488486
http://www.ift.cnr.it
Activities
- Dissection of tumor immune heterogeneity and crosstalk between tumor and immune cells.
- Development of new strategies for local modulation of the tumor immune microenvironment and enhancement of tumor immunogenicity.
- Development of combination therapies to extend the area of efficacy of current immunotherapeutic approaches
Istrument & technologies
- Cell isolation and culture
- CRISPR/Cas9 gene editing
- Gene expression (real-time PCR)
- Protein expression
- Establishment of mouse and/or patient-derived organotypic tumor spheroids
- Multicolor flow cytometry for tumor microenvironment dissection
- In vitro tumor-immune interaction studies (evaluation of activation status, migration, effector function, proliferation)