Francesca Fusco

+39 081 6132 302 (office)
francesca.fusco@igb.cnr.it
https://www.igb.cnr.it/index.php/francesca-fusco/

Institute
Istituto di Genetica e Biofisica “Adriano B. Traverso”
Via Pietro Castellino 111 , 80131 Napoli
www.igb.cnr.it

Ezia Spinosa, Alessia Cirello

Studies of the pathogenesis of human X-linked rare disease and genetic and genomic aspects in genotype-phenotype correlation in human X-linked rare and autoimmunity diseases

• Rosain J, et al., Incontinentia pigmenti underlies thymic dysplasia, autoantibodies to type I IFNs, and viral diseases. J Exp Med. 2024 Nov 4;221(11):e20231152. doi: 10.1084/jem.20231152. Epub 2024 Oct 1. PMID: 39352576; PMCID: PMC11448874
• Asano T, et al. X-linked recessive TLR7 deficiency in ~1% of men under 60 years old with life- threatening COVID-19. Science Immunol. 2021;6(62):eabl4348.
• Bastard P, et al. Autoantibodies neutralizing type I IFNs are present in ~4% of uninfected individuals over 70 years old and account for ~20% of COVID-19 deaths. Science Immunol. 2021 6(62):eabl4340.
• Zhang Q, et al. Inborn errors of type I IFN immunity in patients with life-threatening COVID-19. 2020;370(6515):eabd4570.
• Bastard P, et al. Autoantibodies against type I IFNs in patients with life-threatening COVID-19. Science. 2020 Oct 23;370(6515):eabd4585.

Facs Facility, Microscopy