Cellular Biotechnology Laboratory
Group Leader :Angela Bonura
Institute of Translational Pharmacology (IFT)
Key words: Cancer, Tumour-associated biomarkers, Autoantigens, Multifunctional proteins
Contact
Angela Bonura
+39-091-6809536 | angela.bonura@cnr.it
Istitute
Institute of Translational Pharmacology (IFT)
National Research Council (CNR)
Via Ugo La Malfa 153, 90146 Palermo, Italy.
http://www.ift.cnr.it/
Activities
- Immunomodulatory mechanisms: Parietaria judaica allergens and Ciona intestinalis bioactive peptides as a models.
- iTreg and NK regulatory cells: isolation by magneting cell sorting, gene expression and Flow cytometric analysis.
- Study of phenotypic and functional markers of activated Regulatory cells.
- Cross-talk between regulatory pathways in different
- Antigen specific induced systems. Strategies for Rare cells detection : isolation, expansion, gene expression and Flow cytometric analysis.
- Antigen-specific cytokine responses of innate and adaptive human immune cells
Istrument & technologies
Human immune cell purification and culture, Molecular biology technologies, Magneting cell sorting, FACS