
DNA Vaccine Technology
Group Leader : Monica Rinaldi
Institute of Translational Pharmacologyc – Rome
Contact
Monica Rinaldi
39-06 49934219 | rinaldi@ift.cnr.it
Institute
Institute of Translational Pharmacologyc
Roma, Via Fosso del Cavaliere 100, 00133
Tel. +39 06 49934219
http://www.ift.cnr.it/
Activities
Anti-idiotypic DNA Vaccination in B-cells Lymphoma Preclinic protocols of genetic immunization against tumor-associated antigens Combination therapy: (vaccination+immunotherapy+chemotherapy) DNA vaccine and biotechnology; Targeted therapy: antigen-specific therapy, polyepitope vaccines; Adjuvant therapy;
Cancer immunotherapy; Cancer vaccines; Immunological response.
Istrument & technologies
Development of innovative vaccine formulations for anticancer therapy and/or prevention, intended for clinical application: multigenic plasmid vectors; set-up of in vivo electroporation technology; DNA vaccine immunomodulatory adjuvants; electroporation and prime-boost protocols Naked in vivo gene transfer