NEUROMICS

Group Leaders : Maria Liguori
Institute of Biomedical Technologies (ITB), Bari Unit

Key words : Rare multifactorial neurological disease, Circulating biomarker, Extracellular Vesicle, Transcriptomic, Bioinformatics.

Maria Liguori

Institute
Institute of Biomedical Technologies (ITB), Bari Unit
Via Amendola 122/D, 70125 Bari

Arianna Consiglio, Giorgio Grillo, Nicola Losito, Flavio Licciulli

Liguori M, Bianco A, Introna A, Consiglio A, Milella G, Abbatangelo E, D’Errico E, Licciulli F, Grillo G, Simone IL. An early Transcriptomic Investigation in Adult Patients with Spinal Muscular Atrophy Under Treatment with Nusinersen. J Mol Neurosci. 2024 Sep 26;74(4):89. doi: 10.1007/s12031-024-02251-1 2)
Liguori M, Nuzziello N, Licciulli F, Consiglio A, Simone M, Viterbo RG, Creanza TM, Ancona N, Tortorella C, Margari L, Grillo G, Giordano P, Liuni S, Trojano M. Combined microRNA and mRNA expression analysis in pediatric multiple sclerosis: an integrated approach to uncover novel pathogenic mechanisms of the disease. Hum Mol Genet. 2018 Jan 1;27(1):66-79. doi: 10.1093/hmg/ddx385 3)
Nuzziello N, Liguori M. The MicroRNA Centrism in the Orchestration of Neuroinflammation in Neurodegenerative Diseases. Cells. 2019 Oct 2;8(10):1193. doi: 10.3390/cells8101193 4)
Liguori M, Nuzziello N, Introna A, Consiglio A, Licciulli F, D’Errico E, Scarafino A, Distaso E, Simone IL. Dysregulation of MicroRNAs and Target Genes Networks in Peripheral Blood of Patients With Sporadic Amyotrophic Lateral Sclerosis. Front Mol Neurosci. 2018 Aug 28;11:288. doi: 10.3389/fnmol.2018.00288. 5) Nuzziello N, Blonda M,
Licciulli F, Liuni S, Amoruso A, Valletti A, Consiglio A, Avolio C, Liguori M. Molecular Characterization of Peripheral Extracellular Vesicles in Clinically Isolated Syndrome: Preliminary Suggestions from a Pilot Study. Med Sci (Basel). 2017 Sep 18;5(3):19. doi: 10.3390/medsci5030019

PRIN 2017 “NanoTechVax Tackling biological barriers to antigen delivery by nanotechnological vaccines”. Prot. 20173ZECCM.
H2020 ETN project “ENDONANO: Quantitative detection of bacterial ENDOtoxin by novel NANOtechnological approaches”. H2020-MSCA-ITN-2018 – EID- 812661.
PNRA 2018 “Impact of the Antarctic environments on human homeostasis, psychology, physiology and immunology”
PNRA 2016 “Effects of extreme environments on psychophysiology, energy metabolism and immunity: neuropsychological, immunohistochemical, proteomic and fMRI studies”

The ITB Unit in Bari is part of the following research Infrastructures:

ELIXIR-CNRBiOmics, the Italian Node of ELIXIR (ELIXIR-IT) of the European Research Infrastructure for Life Science (PIR01_00017).
ELIXIRNextGenITA, consolidation of the Italian Infrastructure for Omics and Bioinformatics (PNRR_IR0000010).