Nadia Lampiasi
+39 091 6809513 |  nadia.lampiasi@irib.cnr.it

Istitute
Institute for Biomedical Research and Innovation
Via Ugo La Malfa 153, 90146 Palermo
Tel. +39 091 6809 194
https://www.irib.cnr.it/

• Rosa Bonaventura,
• Irene Deidda,
• Roberta Russo,
• Francesca Ziro
  

The focus of our research concerns the molecular mechanisms of activation and response of monocytes-macrophages in the physiological and pathological inflammatory reaction. We study the polarization of macrophages in a pro- and anti-inflammatory sense, the activation signaling for the production of cytokines, the main transcription factors involved, the cytokines produced and oxidative stress. We study the possibility of reprogramming/re-educating macrophages in a pro- or anti-inflammatory sense depending on the context, also through the use of natural and synthetic immunomodulators.

New Strategies for Macrophage Re-Education in Cancer: An Update. Lampiasi N. Int J Mol Sci. 2024 Mar 18;25(6):3414. doi: 10.3390/ijms25063414.

Inflammation and the Potential Implication of Macrophage-Microglia Polarization in Human ASD: An Overview. Lampiasi N, Bonaventura R, Deidda I, Zito F, Russo R. Int J Mol Sci. 2023 Jan 31;24(3):2703. doi: 10.3390/ijms24032703.

A new ginger extract characterization: Immunomodulatory, antioxidant effects and differential gene expression Russo R, Costa MA, Lampiasi N, Chiaramonte M, Provenzano A, Mangione MR, Passantino R, Zito F. Food Bioscience Volume 53, June 2023, 102746

Interactions between Macrophages and Mast Cells in the Female Reproductive System. Lampiasi N. Int J Mol Sci. 2022 May 12;23(10):5414. doi: 10.3390/ijms23105414.

Gene Expression Profiling of NFATc1-Knockdown in RAW 264.7 Cells: An Alternative Pathway for Macrophage Differentiation. Russo R, Mallia S, Zito F, Lampiasi N. Cells. 2019 Feb 7;8(2):131. doi: 10.3390/cells8020131.

Flow Cytometer, GloMax, Fluorescence Microscopes, qPCR, Chemidoc